Diabetes

A novel insulin accelerant

Insulin levels rise after eating a meal, signaling uptake of circulating glucose by skeletal muscle. In individuals with diabetes this process is often impaired—a condition known as insulin resistance.

Oncology & Cancer

Study challenges long-standing concept in cancer metabolism

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.

Diabetes

Discovery may revolutionise diabetes treatment

Research published in the journal Nature Medicine on Monday by my team provides hope for a new approach to treating type 2 diabetes. In animal models of the disease, our treatment restores natural control of blood sugar.

Diabetes

Exercise impacts adipose tissue via eNOS mechanisms

(HealthDay)—There is a crucial role played by endothelial nitric oxide synthase (eNOS)-derived nitric oxide (NO) in the metabolic adaptation of subcutaneous adipose tissue to exercise training, according to an animal study ...

Diabetes

Exercise ups mitochondrial biogenesis in adipose tissue

(HealthDay)—Exercise training increases mitochondrial biogenesis, mitochondrial DNA (mtDNA) content, and glucose uptake in the subcutaneous adipose tissue of wild type, but not endothelial nitric oxide synthase (eNOS) knockout ...

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