Three different disease-causing viruses -- poliovirus, coxsackievirus, and hepatitis C -- rely on their unwilling host for the membrane platforms enriched in a specific lipid, phosphatidylinositol 4 phosphate (PI4P) on which ...
Dec 7, 2011
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The failure of pancreatic beta cells to release appropriate amounts of insulin in response to rising blood glucose levels is a hallmark of type 2 diabetes.
Aug 1, 2019
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Researchers at Duke-NUS Medical School have discovered the regenerative capabilities of injured cellular protrusions from dormant neural stem cells (NSCs) in fruit flies. Published in Developmental Cell, the findings establish ...
Aug 8, 2023
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A cellular component known as the Golgi apparatus may play a role in how lung cancer metastasizes, according to researchers at The University of Texas MD Anderson Cancer Center whose findings were reported in the Nov. 21 ...
Nov 21, 2016
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Peripheral membrane proteins temporarily bind to cell membranes, a necessary step for them to be able to fulfill their biological function. To do this, certain enzymes that catalyze their lipid modification come into action. ...
Apr 25, 2022
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Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. ...
Mar 7, 2018
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To transport substances from the site of their production to their destination, the body needs a sophisticated transport and sorting system. Various receptors in and on the cells recognize certain molecules, pack them and ...
Oct 18, 2012
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Many proteins undergo an assembly line-style process of glycosylation as they travel from a cellular structure called the endoplasmic reticulum (ER) to the Golgi apparatus and on through its various compartments, after which ...
Aug 27, 2014
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(Medical Xpress)—To remain healthy, the body's cells must properly manage their waste recycling centers. Problems with these compartments, known as lysosomes, lead to a number of debilitating and sometimes lethal conditions.
Feb 20, 2014
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Many proteins at the cell surface are 'decorated' with carbohydrate molecules called glycans. Changes in a cell's glycan profile can greatly alter how it behaves and interacts with its environment, and abnormalities in this ...
Jan 29, 2014
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