(HealthDay) -- Patients with hematologic malignancies undergoing an HLA-mismatched unrelated donor (MMUD) reduced-intensity conditioning (RIC) hematopoietic stem cell transplantation (HSCT) may benefit from a prophylactic, ...
Aug 8, 2012
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Doctors are one step closer to having a risk biomarker to alert them to which of their pediatric stem cell transplant patients are likely to experience a potentially deadly side effect called sinusoidal obstruction syndrome ...
May 22, 2023
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New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.
Jan 30, 2023
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Joseph Pidala, M.D., M.S., assistant member of the Blood and Bone Marrow Transplant and Immunology programs at Moffitt Cancer Center, and colleagues from the Chronic Graft-Versus-Host Disease Consortium have determined that ...
Jun 17, 2013
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Researchers in the Center for Cell and Gene Therapy at Baylor College of Medicine, Houston Methodist and Texas Children's Hospital have found that a single dose of an otherwise harmless drug can safely control the severe ...
May 14, 2015
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Allogeneic hematopoietic cell transplantation (HCT) is a commonly used curative therapy for individuals with inborn errors of immunity (IEI). HCT involves introducing stem cells from a compatible donor with the aim of replacing ...
Jul 26, 2024
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Researchers at Mount Sinai Health System have discovered a way to predict whether blood cancer patients who received a bone marrow transplant will develop graft-versus-host disease, a common and often lethal complication, ...
Feb 9, 2017
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Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have determined that a specific type of immune cell—type II innate lymphoid cells (ILC2s)—can change its characteristics and functions after a cancer ...
Jul 25, 2024
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Stanford University School of Medicine investigators have identified a clutch of cells that—if seen in a male patient's blood after receiving a brand-new immune system in the form of a bone-marrow transplant from a female ...
Feb 4, 2013
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A new protein biomarker test platform developed by researchers at the University of Michigan and Indiana University promises to improve diagnostic testing. The test can accurately and simultaneously measure multiple proteins ...
Jul 16, 2014
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