A team led by researchers at the Perelman School of Medicine at the University of Pennsylvania has used advanced techniques to show that, in a key memory region of the brain called the hippocampus, immature, plastic neurons ...
Jul 18, 2022
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Our brains can distinguish highly similar patterns, thanks to a process called pattern separation. How our brains separate patterns is, however, not yet fully understood. Using a full-scale computer model of the dentate gyrus, ...
Dec 16, 2021
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Biomedical engineers developed a technique to observe wound healing in real time, discovering a central role for cells known as fibroblasts. The work, reported in APL Bioengineering, is the first demonstration of a wound ...
Jan 19, 2021
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Imagine going to a café you have never been to. You will remember this new environment, but when you visit it again and again fewer new memories about the environment will be formed, only the things that changed will be ...
Oct 15, 2020
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The dentate gyrus is part of the hippocampus, an area of the brain that plays a critical role in memory formation, and contains neural stem cells that develop into other cell types, such as granule cells, mossy cells, and ...
Sep 24, 2020
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How do you keep orientation in a complex environment, like the city of Vienna? You can thank your brain's 'global positioning system,' the hippocampus, for this sense of orientation. To further understand its functions, scientists ...
Aug 6, 2020
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St. Jude Children's Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum. ...
Sep 11, 2019
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A team of researchers affiliated with several institutions in the U.S. reports that newly generated nerve cells in the brain's dentate gyrus impact older nerve cells in two ways. In their paper published in the journal Science, ...
Cells' metabolic needs are not uniform across the brain, researchers have learned. "Knocking out" an enzyme that regulates mitochondria, cells' miniature power plants, specifically blocks the development of the mouse cerebellum ...
Oct 10, 2018
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Few treatments exist for neurodegenerative diseases that progressively rob a person's ability to move and think, yet the results of a new study could potentially open additional approaches for exploration.
Sep 7, 2018
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