Scientists identify Achilles heel of lung cancer protein
Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.
Mar 19, 2024
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Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.
Mar 19, 2024
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The Organoid group at the Hubrecht Institute has identified a new link between FBXW7 mutations and epidermal growth factor receptor (EGFR) signaling activity. The FBXW7 gene is commonly mutated in colorectal cancer and such ...
Mar 18, 2024
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Targeting two brain tumor-associated proteins—rather than one—with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain ...
Mar 13, 2024
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Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment. Researchers ...
Feb 8, 2024
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Lung adenocarcinoma is the most common lung cancer and the cause of most cancer-related deaths in the United States. There are several ways lung adenocarcinoma can arise, one of which is a mutation in a protein called EGFR ...
Feb 7, 2024
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Glioblastoma is the most common type of brain tumor that affects adults and, unfortunately, still remains incurable. In a new study, researchers have demonstrated that a specific mitochondrial protein plays an important role ...
Oct 17, 2023
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Researchers at the University of Oulu have made a discovery in breast cancer research. They demonstrated that the extracellular matrix protein collagen XVIII significantly promotes breast cancer progression and metastasis. ...
Oct 17, 2023
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A new editorial paper titled "Potential repurposing of DPP4 inhibitors for target therapy resistance in renal cell carcinoma" has been published in Oncotarget.
Sep 20, 2023
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An international team of researchers has demonstrated that a combination of inhibitors may suppress tumor growth and prevent relapse in patients with certain cancers, including head and neck squamous cell carcinoma and lung ...
Sep 12, 2023
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Cisplatin is a potent chemotherapeutic agent used to treat various cancers, including cervical cancer. But the continued use of cisplatin can lead to the development of cisplatin resistance and other side effects, like chemotherapy-induced ...
Jul 20, 2023
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