Oncology & Cancer

New guidelines for managing mucositis now available

Updated clinical practice guidelines for managing mucositis, a very common and often debilitating complication of cancer therapy, was recently published in the journal Cancer. Patients experiencing mucositis often require ...

Medical research

New treatment targets found for blinding retinal disease

When the eye isn't getting enough oxygen in the face of common conditions like premature birth or diabetes, it sets in motion a state of frenzied energy production that can ultimately result in blindness, and now scientists ...

Diseases, Conditions, Syndromes

Pulmonary fibrosis treatment shows proof of principle

A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with ...

Oncology & Cancer

New drug targets for lethal brain cancer discovered

More than 200 genes with novel and known roles in glioblastoma—the most aggressive type of brain cancer—offer promising new drug targets. Researchers from the Wellcome Sanger Institute, Addenbrooke's Hospital and their ...

Immunology

St18 is a negative regulator of VEGF

Pro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopolysaccharide (LPS) are known to activate NF-kB. NF-kB is a master regulator of inflammation and induces pro-inflammatory cytokines. Although ...

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