Through millions of years of evolutionary refinement, the human body has developed a sophisticated surveillance mechanism—the immune system. This intricate network is constantly scanning the body for invaders such as bacteria, ...
Apr 17, 2024
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A new research paper titled "Systemic changes induced by autologous stem cell ovarian transplant in plasma proteome of women with impaired ovarian reserves" has been published in Aging.
Jan 9, 2024
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New experimental evidence suggests that substances known as narrow-spectrum Wnt signaling inhibitors—which could have fewer side effects than other related substances—are capable of suppressing the growth of breast cancer ...
Nov 9, 2023
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As we age, many of us will eventually need hearing aids. In some cases, the reason for this may be a signaling pathway that controls auditory sensory cell function and is downregulated with age. Researchers at the University ...
Oct 5, 2023
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Investigators led by Kathleen Green, Ph.D., the Joseph L. Mayberry, Sr., Professor of Pathology and Toxicology, have discovered novel intercellular "crosstalk" between epidermal keratinocytes and melanoma cells that promote ...
Sep 22, 2023
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Cisplatin is a potent chemotherapeutic agent used to treat various cancers, including cervical cancer. But the continued use of cisplatin can lead to the development of cisplatin resistance and other side effects, like chemotherapy-induced ...
Jul 20, 2023
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Globally, human hepatocellular carcinoma (HCC) is the sixth most common cancer and the fourth leading cause of cancer-related mortality. The worldwide incidences of HCC have been on the rise in recent decades. Unfortunately, ...
May 10, 2023
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Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medications. This is the case, for example, with alpelisib, a drug that has been approved for ...
Apr 11, 2023
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Much of the research on new cancer treatments in the last two decades has focused on genetic targets that allow cancers to grow and spread by altering cell signaling or shutting off tumor suppressors. There is a growing body ...
Apr 7, 2023
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A new research paper, titled "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer," was published in Genes & Cancer on March ...
Mar 24, 2023
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