Heart attack survivors may think the worst is behind them. But many later develop heart failure, a progressive disease marked by shortness of breath and swelling in the legs. Symptoms can prevent patients from working, exercising—even ...
Jan 28, 2019
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119
Heart muscle cells need exercise—even when they grow outside the human body. A new device designed by U of T Engineering researchers uses a rigorous training regimen to grow small amounts of cardiac tissue and measure how ...
Jan 24, 2019
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20
The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be used to effectively treat long-term, chronic conditions. A research team led by Dongsheng ...
Jan 9, 2019
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A detailed cell-by-cell map of all dividing cells in the adult murine heart before and after myocardial infarction was created using advanced molecular and genetic technologies in a combined research effort led by Hans Clevers ...
Dec 3, 2018
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Repairing heart muscle damaged by a heart attack or other cardiovascular diseases is one of the "holy grails" for cardiovascular scientists. The ability to repair heart muscle—especially by using a person's own cells—would ...
Nov 30, 2018
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An unexpected finding that links a structural heart protein to gene regulation following heart stress suggests potential new avenues for developing heart failure therapies.
Nov 8, 2018
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45
A lab team led by Nobel Prize winner Dr. Andrew Schally at the Miami Veterans Affairs Healthcare System and the University of Miami showed that a synthetic compound based on a brain hormone spurred the growth of cancer cells ...
Nov 6, 2018
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Individual cells within the same heart cope differently with high blood pressure, according to a study in human cells and mice by a team of cardiologists and computational biologists at the University of Tokyo. This is the ...
Oct 30, 2018
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51
Scientists around the world have been trying to replace damaged heart tissue using lab-made heart-muscle cells (cardiomyocytes), either injecting them into the heart or applying patches laced with the cells. But results to ...
Sep 27, 2018
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84
About one person out of 500 has a heart condition known as hypertrophic cardiomyopathy (HCM). This condition causes thickening of the heart muscle and results in defects in the heart's electrical system. Under conditions ...
Sep 20, 2018
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