Diseases, Conditions, Syndromes
Snuggling your pet hedghog may spread salmonella, CDC warns
(HealthDay)—They're cute, but cuddling a pet hedgehog could transmit potentially deadly salmonella, U.S. health officials warned Friday.
Jan 28, 2019
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Page 4 - News tagged with hedgehog
Genetics
The puzzle of a mutated gene lurking behind many Parkinson's cases
Genetic mutations affecting a single gene play an outsized role in Parkinson's disease. The mutations are generally responsible for the mass die-off of a set of dopamine-secreting, or dopaminergic, nerve cells in the brain ...
Nov 15, 2018
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Oncology & Cancer
Study helps explain launch switch for most common malignant pediatric brain tumor
A delicate balance during brain development could have profound implications for understanding and treating medulloblastoma, the most common malignant brain tumor affecting children.
Mar 29, 2018
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Oncology & Cancer
Hedgehog signaling proteins keep cancer stem cells alive
Researchers from Charité - Universitätsmedizin Berlin have discovered that the survival of cancer stem cells is dependent on the Hedgehog signaling pathway. Targeting this pathway had previously shown no effect on the growth ...
Jan 22, 2018
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Oncology & Cancer
Atoh1, a potential Achilles' heel of Sonic Hedgehog medulloblastoma
Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side effects, including psychiatric disorders, growth retardation ...
Dec 12, 2017
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Oncology & Cancer
New pathway identified as a target for precision medicine against a common brain tumor
St. Jude Children's Research Hospital scientists have discovered a promising target for precision medicines to block a mechanism that drives several cancers, including about 30 percent of cases of the brain tumor called medulloblastoma. ...
Nov 2, 2017
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Oncology & Cancer
Genomic analysis of liver cancer reveals unexpected genetic players
Liver cancer has the second-highest worldwide cancer mortality, and yet there are limited therapeutic options to manage the disease. To learn more about the genetic causes of this cancer, and to identify potential new therapeutic ...
Jun 16, 2017
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Oncology & Cancer
Metastatic breast cancer cells use hedgehog to 'evilize' docile neighbors
A University of Colorado Cancer Center study published today in Nature Communications shows that metastatic breast cancer cells signal neighboring cells in ways that allow otherwise anchored cells to metastasize. The work ...
Jun 12, 2017
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Genetics
Taste bud maintenance in mice requires Hedgehog signaling
Disruptions in the Hedgehog signaling pathway can interfere with taste bud maintenance in mice, potentially explaining why some cancer patients experience a loss of taste during treatment with Hedgehog-blocking drugs. Charlotte ...
Nov 28, 2016
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Genetics
Scientists find cause of facial widening defects
Widening across the forehead and nose occurs when loss of cilia at the surface of the cells disrupts internal signaling and causes two GLI proteins to stop repressing midfacial growth. Ching-Fang Chang and Samantha Brugmann ...
Nov 1, 2016
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