Immunology

Toxin floats on lipid rafts

Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...

Diseases, Conditions, Syndromes

Helicobacter pylori infection permanently changes gastric environment

The make-up of the human gut flora is highly individual and extremely diverse. However, when a Helicobacter pylori infection is present, this bacterium displaces all other bacteria in the gastrointestinal tract, leaving only ...

Oncology & Cancer

Landmark genetic study better predicts stomach cancer

A research team led by National University Health System (NUHS) and Duke-NUS Medical School has used genomic technologies to better understand intestinal metaplasia (IM), a known risk factor for gastric (stomach) cancer. ...

Diseases, Conditions, Syndromes

PPI-gastric cancer link remains after H. pylori eradication

(HealthDay)—Long-term proton pump inhibitor (PPI) use is associated with increased risk of gastric cancer (GC) even after Helicobacter pylori (HP) eradication therapy, according to a study published online Oct. 31 in Gut.

Diseases, Conditions, Syndromes

Research says H. pylori needs much closer attention

It was long thought that gastric ulcers and other digestive woes were brought about by stress. But in 2005, clinical fellow Barry J. Marshall and pathologist J. Robin Warren were awarded the Nobel Prize in Physiology or Medicine ...

Diseases, Conditions, Syndromes

Vonoprazan-based triple tx feasible for H. pylori

(HealthDay)—The potassium-competitive acid blocker vonoprazan-based triple therapy seems safe and effective compared with conventional proton pump inhibitor (PPI)-based triple therapy as first-line treatment against Helicobacter ...

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