A study led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) has found that CD4+ T cells, traditionally called 'helper T cells' for their role in aiding the activation of other immune cells, are ...
Jan 19, 2024
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Cytomegalovirus (CMV) is a pathogen that likes to lurk. Most adults already carry CMV, and they show no symptoms at all. The trouble comes when the virus infects a pregnant person for the first time and passes through the ...
Jan 19, 2024
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After COVID vaccination, it usually takes weeks for our bodies to develop protective antibody responses. Imagine, however, a vaccine that speeds up the production of antibodies against SARS-CoV-2, the virus that spreads COVID-19.
Jan 17, 2024
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Checkpoint inhibitors that activate the immune system to target cancer cells for destruction have revolutionized the treatment landscape for patients with advanced melanoma, leading to more options and improved patient survival. ...
Dec 8, 2023
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Investigator Ming Li, Ph.D., has dedicated his career to understanding the intricate workings of the immune system—both in general and for the critical role it plays in cancer.
Nov 14, 2023
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Conventional wisdom lays out two major roles for the major histocompatibility complex (MHC): Class I MHC (MHC-I) displays peptide fragments of proteins from within the cell on the cell surface and elicits a response from ...
Oct 12, 2023
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HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops. These reservoirs have long been thought to be dormant, ...
Sep 13, 2023
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Scientists are on the hunt for a unique set of mutations, called "neoantigens," that let the immune system distinguish tumor cells from normal cells. Their goal is to help the immune system react to neoantigens and target ...
Sep 4, 2023
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Respiratory viruses like influenza virus (flu), SARS-CoV-2 (which causes COVID) and respiratory syncytial virus (RSV) can make us sick by infecting our respiratory system, including the nose, upper airways and lungs.
Jul 30, 2023
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Restoring and improving gut health may be key to slowing HIV progression to AIDS, according to a new study by University of Pittsburgh infectious diseases scientists published today in the journal JCI Insight.
Jul 24, 2023
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