New genetic weapons challenge sickle cell disease
Help for patients with sickle cell disease may soon come from gene editing to fix the mutation that causes the disease and boost the patient's own protective fetal hemoglobin.
Jun 3, 2019
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Help for patients with sickle cell disease may soon come from gene editing to fix the mutation that causes the disease and boost the patient's own protective fetal hemoglobin.
Jun 3, 2019
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A healthy adult makes about 2 million blood cells every second, and 99 percent of them are oxygen-carrying red blood cells. The other one percent are platelets and the various white blood cells of the immune system. How all ...
Mar 21, 2019
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RUDN researchers have proposed freezing parts of human umbilical cord, among other things, to obtain stem cells. Unlike conserved umbilical blood, the perivascular tissue of the umbilical cord (Wharton's jelly) is an effective ...
Feb 21, 2019
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An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bone marrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at ...
Feb 11, 2019
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The bone marrow disease myelofibrosis is stimulated by excessive signaling from vitamin D and immune cells known as macrophages, reveals a Japanese research team. These findings could help to develop alternative treatments ...
Feb 8, 2019
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Functional B-1 cells derived from mouse embryonic stem cells are capable of long-term engraftment and secrete natural antibodies after transplantation in mice, researchers report February 7th in the journal Stem Cell Reports. ...
Feb 7, 2019
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(HealthDay)—For patients with relapsing-remitting multiple sclerosis (MS), nonmyeloablative hematopoietic stem cell transplantation (HCST) is associated with prolonged time to disease progression compared with disease-modifying ...
Jan 16, 2019
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New research from the Stowers Institute for Medical Research has identified the backup for an important biological system—the hematopoietic system, whose adult stem cells constantly replenish the body's blood supply.
Jan 15, 2019
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Aging is characterized by increases in inflammation and decreases in stem cell function. The relationship between these processes remains incompletely understood. Researchers of the Leibniz Institute on Aging (FLI) in Jena, ...
Dec 14, 2018
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The human intestine may provide up to 10 percent of blood cells in circulation from its own reservoir of blood-forming stem cells, a surprising new study from researchers at Columbia University Vagelos College of Physicians ...
Nov 29, 2018
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