New research from the Stowers Institute for Medical Research has identified the backup for an important biological system—the hematopoietic system, whose adult stem cells constantly replenish the body's blood supply.
Jan 15, 2019
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Aging is characterized by increases in inflammation and decreases in stem cell function. The relationship between these processes remains incompletely understood. Researchers of the Leibniz Institute on Aging (FLI) in Jena, ...
Dec 14, 2018
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The human intestine may provide up to 10 percent of blood cells in circulation from its own reservoir of blood-forming stem cells, a surprising new study from researchers at Columbia University Vagelos College of Physicians ...
Nov 29, 2018
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Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather, the location of DNA mutations is relevant. Using ...
Nov 29, 2018
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Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.
Nov 27, 2018
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Human SH2D1A mutations resulting in X-linked lymphoproliferative syndrome type 1 (XLP1) are associated with a unique susceptibility to the Epstein-Barr virus (EBV), which may lead to fatal infectious mononucleosis (FIM). ...
Nov 12, 2018
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Researchers led by a UCLA bioengineer have developed a therapy—based on two types of cells joined into a single unit—that could help strengthen existing treatments for acute myeloid leukemia. One of the cells is a blood ...
Oct 30, 2018
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Patients with blood cancers such as leukemia and lymphoma are often treated by irradiating their bone marrow to destroy the diseased cells. After the treatment, patients are vulnerable to infection and fatigue until new blood ...
Oct 24, 2018
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Hematopoietic stem cell transplantation (HSCT) is the treatment of choice for many patients with malignant and non-malignant hematological diseases, such as leukemia and multiple myeloma. The success of recent advances in ...
Sep 19, 2018
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Your body's blood cells are manufactured by hematopoietic stem cells in bone marrow. But just as regular, mature cells can become cancerous, so too can stem cells. When hematopoietic stem cells mutate in specific ways, the ...
Sep 12, 2018
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