Diseases, Conditions, Syndromes

Investigating acute hepatitis of unknown origin in children

Since Fall 2021, an increasing number of unexplained cases of severe acute hepatitis have been reported in children. Epidemiologic investigation is ongoing, and, to date, a cause of these outbreaks has not been identified. ...

Neuroscience

Studying herpes encephalitis with mini-brains

About 3.7 billion people carry the herpes simplex virus-1 in our nerve cells where it lies quiescent until triggered by stress or injury. When activated, its symptoms are usually mild, limited to cold sores or ulcers in our ...

Immunology

Study shows immune cells have a backup mechanism

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral ...

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