Diseases, Conditions, Syndromes

Herpes simplex virus linked to frailty, mortality

(HealthDay)—For older women, herpes simplex virus antibody levels are associated with incident frailty and mortality, according to a study published online April 30 in the Journal of the American Geriatrics Society.

Alzheimer's disease & dementia

3-D brain-like tissue model links Alzheimer's disease with herpes

Engineers and scientists led by Tufts University used a three-dimensional (3-D) human tissue culture model mimicking the components and conditions in the brain to demonstrate a possible causal relationship between sporadic ...

Diseases, Conditions, Syndromes

Scientists advance understanding of herpesvirus infection

Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle ...

Oncology & Cancer

Unusual treatment shows promise for kids with brain tumors

For decades, a deadly type of childhood cancer has eluded science's best tools. Now doctors have made progress with an unusual treatment: Dripping millions of copies of a virus directly into kids' brains to infect their tumors ...

Medical research

Stress wakes up sleeping herpes viruses – but how?

Hiding their DNA genome inside the nuclei of the infected cells, the herpes viruses establish a lifelong infection in humans. Poorly defined stress conditions are known to wake up these parasites from their latent phase and ...

Diseases, Conditions, Syndromes

New worldwide estimates for herpes simplex virus type 2 published

New global estimates for herpes simplex virus type 2 show that over 400-million people worldwide were infected with the virus in 2012. The estimates underline the extent to which herpes simplex virus type 2 – the virus ...

Diseases, Conditions, Syndromes

Preclinical evaluation of a vaccine against herpes viruses

Oral and genital herpes are caused by the herpes simplex virus type 1 (HSV-1) and the herpes simplex virus type 2 (HSV-2), which both cause lifelong infection. HSV-2 infection is associated with increased risk for HIV infection. ...

Diseases, Conditions, Syndromes

Research shows progress toward a genital herpes vaccine

An investigational vaccine protected some women against infection from one of the two types of herpes simplex viruses that cause genital herpes, according to findings in the New England Journal of Medicine.

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