Inflammatory disorders

Rethinking an inflammatory receptor's obesity connection

Toll-like receptor 4 (TLR4) is a protein that plays a vital role in the body's immune response by sensing the presence of infection. It has long been thought to also sense particular types of fats, which suggested a mechanism ...

Medical research

Receptor protein in the brain controls the body's fat 'rheostat'

Scientists at the University of Michigan and Vanderbilt University have identified the function of a protein that has been confounding metabolism researchers for more than two decades. And it may have implications both for ...

Medical research

Obesity, infertility and oxidative stress in mouse egg cells

Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes. In a recent paper published in Molecular ...

Medical research

Innovative technique converts white fat to brown fat

Brown fat tissue in the body can burn enormous amounts of energy to generate heat, and studies in humans and animals have suggested that increasing the amount of healthy brown fat might help weight management and reduce symptoms ...

Pediatrics

How maternal diet could change the infant gut microbiome

UNSW Sydney researchers presenting at the Developmental Origins of Health and Disease Conference in Sydney this week highlighted evidence that suggest changes to a mother's microbiome, or gut health, brought on by obesity ...

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