Mechanical forces play a critical role in myelination, the formation of the protective coating that neurons need to function, researchers at the University at Buffalo have discovered.
Jun 7, 2016
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New Peter Mac research shows that two molecular pathways that drive cancer development, work together to increase the production of fats inside cancer cells.
Feb 25, 2022
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UT Southwestern researchers have made a major advance in uncovering the biology of how thousands of disfiguring skin tumors occur in patients troubled by a genetic disorder called neurofibromatosis type 1 (NF1). This scientific ...
Oct 23, 2018
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It's known that cancer involves unchecked cell growth and that a biological pathway that regulates organ size, known at the Hippo pathway, is also involved in cancer. It's further known that a major player in this pathway, ...
Nov 20, 2018
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The Hippo pathway is an important biological tumor suppressor program that controls cell growth and organ size in humans. Cancer cells have been found to frequently deactivate Hippo signaling in order to achieve increased ...
Apr 4, 2019
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Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in ...
Dec 1, 2016
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With an estimated twenty-thousand protein-coding genes in the human genome, pinpointing a specific gene or pathway responsible for a particular disease can be like finding a needle in the proverbial haystack. This has certainly ...
Oct 17, 2018
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Like detectives tracking a serial killer, St. Jude Children's Research Hospital scientists have identified a novel mechanism that may help promote the growth and spread of solid tumors. The findings appeared online Oct. 25 ...
Oct 31, 2018
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After a heart attack, or myocardial infarction, a patient's long-term prognosis depends on the ability of the heart tissue to heal and remodel. Immune system activation and inflammatory responses that occur in the aftermath ...
Feb 6, 2017
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The early development of embryos is not well understood. One necessary stage is the formation of the blastocyst, a collection of cells present by about 4 days after fertilization of the egg, before implantation in the uterus. ...
Jun 27, 2019
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