A recent study has reported that changes in mice sperm microRNAs brought about by aging may affect the growth and development of offspring. The finding adds to the growing literature on the effects of paternal aging on offspring.
Jan 12, 2024
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Chromatin states and their associated epigenetic information play a crucial role in maintaining the identity of cells as they divide. Histone post-translational modifications (PTMs) are important determinants of the cellular ...
Jun 16, 2023
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The dream of a drug that can help ameliorate the stress associated with durable traumatic memories, in order to treat disorders such as PTSD, has come a step closer to reality, according to a preclinical study led by researchers ...
Aug 22, 2022
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EPFL scientists have discovered how an anti-cancer drug could be repurposed to improve memory. It does so by supporting the cell's ability to read the very genes that are important for learning. The epigenetic mechanism of ...
Jun 13, 2022
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Research led by Peter Mac and published in Cancer Discovery has found a new combination therapy for acute myeloid leukemia (AML) that shows greater potency in a preclinical study than either drug used alone.
Jun 1, 2022
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Gene editing may be a potential treatment for anxiety and alcohol use disorder in adults who were exposed to binge drinking in their adolescence, according to the results of an animal study published in the journal Science ...
May 4, 2022
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Researchers led by Azusa Inoue at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a gene responsible for prenatal death when critical transgenerational instructions are missing from egg cells. ...
Apr 27, 2022
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Mutations in a histone regulator protein are linked to both a rare neurodevelopmental disorder and to some cancers, according to a study published in the journal Genes and Development.
Dec 17, 2021
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How do cis-regulatory genome elements regulate gene expression, what are the critical components involved, and can we therapeutically target them? By investigating how corepressors modulate enhancers and silencers during ...
Jan 27, 2021
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106
Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic and epigenetic factors. Despite a few previously reported aging-associated ...
Jan 8, 2021
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