The brain chemical serotonin, a neurotransmitter long known for its role in passing signals between neurons in the brain, can also regulate expression of genes within neurons in an unexpected way, according to research conducted ...
Mar 13, 2019
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Although certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD ...
Mar 5, 2018
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Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the ...
Mar 1, 2017
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To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery. Now, new research shows how ...
Nov 28, 2016
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Why gestational diabetes leads to type 2 diabetes has baffled medical science for decades, but new research led by Deakin University has shown the answer could be in our genes' ability to change their behaviour due to signals ...
May 17, 2016
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(Medical Xpress)—High school biology taught us that we inherit certain traits from our parents that are pre-determined. But what if you could change how these genes play out by taking certain drugs or better yet, just changing ...
Sep 16, 2014
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A*STAR researchers show that changes in histone modifications accelerate a type of stomach tumor known as gastric adenocarcinoma—a cancer that occurs more frequently in Asian populations than Western populations.
Sep 10, 2014
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At a glance, DNA is a rather simple sequence of A, G, C, T bases, but once it is packaged by histone proteins into an amalgam called chromatin, a more complex picture emerges. Histones, which come in four subtypes—H2A, ...
Jan 15, 2014
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Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study. Published ...
Aug 12, 2013
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In degenerative brain diseases and after stroke, nerve cells die while their support cells activate the brain's immune system to cause further damage. Now Jonathan Gilthorpe, Adrian Pini and Andrew Lumsden at the MRC Centre ...
Jul 23, 2013
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