Medical research
DNA regulator offers new hope for Hodgkin lymphoma treatment
Researchers at The Australian National University (ANU) have discovered how a DNA-binding protein sustains Hodgkin lymphoma.
Jul 21, 2021
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Page 4 - News tagged with histones
Genetics
Inheriting acquired traits requires trailblazer modifications to unfertilized eggs
An epigenetic study at the RIKEN Center for Integrative Medical Sciences shows that in mouse egg cells, modifications to histone H2A at lysine 119 lay the groundwork for inherited DNA functional modifications from the mother.
Apr 7, 2021
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Oncology & Cancer
Aging cells in abdominal fluid cause increased peritoneal dissemination of gastric cancer
Through an analysis of cellular components (cell fractions) from malignant ascites (fluid buildup in the abdomen caused by gastric cancer), a research collaboration based in Kumamoto University (Japan) has demonstrated that ...
Mar 23, 2021
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Medical research
Research team profiles histone mutational landscape of human cancers
Researchers in the Muir Lab at Princeton University's Department of Chemistry have completed the first comprehensive analysis of cancer-associated histone mutations in the human genome, featuring both biochemical and cellular ...
Mar 1, 2021
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Genetics
Epigenetic mechanisms that regulate macrophage inflammation discovered
How do cis-regulatory genome elements regulate gene expression, what are the critical components involved, and can we therapeutically target them? By investigating how corepressors modulate enhancers and silencers during ...
Jan 27, 2021
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Medical research
Scientists develop new gene therapy strategy to delay aging
Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic and epigenetic factors. Despite a few previously reported aging-associated ...
Jan 8, 2021
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Medical research
New drug to combat global killer sepsis
A promising new drug to combat sepsis has been developed by researchers at The Australian National University (ANU), potentially saving millions of lives each year.
Dec 17, 2020
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Genetics
Mutations in key chromosome protein may lead to neurodevelopmental issues
Researchers from Children's Hospital of Philadelphia (CHOP) have demonstrated that newly mutated variants of a key protein involved in supporting chromosomes result in several issues ranging from developmental delays to epilepsy ...
Dec 3, 2020
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Medical research
Enzyme could prove effective in treating tumors and inflammatory diseases in lung: study
Findings from a research study, led by scientists at Henry Ford, published in the latest issue of Nature Communications suggest an enzyme could play an important role in the treatment of cancer and autoimmune diseases in ...
Aug 4, 2020
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Diseases, Conditions, Syndromes
Research on brain swelling in children with cerebral malaria reveals potential new treatment approach
Through investigating the causes of brain swelling in cerebral malaria—a devastating parasitic disease that is fatal for one in five children—scientists have found a potential new treatment approach that could be safely ...
Jun 25, 2020
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