Neuroscience

Human skin cells reprogrammed directly into brain cells

Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington's disease, an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one ...

Oncology & Cancer

Fruit flies reveal features of human intestinal cancer

Researchers in Spain have determined how a transcription factor known as Mirror regulates tumour-like growth in the intestines of fruit flies. The scientists believe a related system may be at work in humans during the progression ...

Alzheimer's disease & dementia

DNA methylation involved in Alzheimer's disease

A new study led by researchers at Brigham and Women's Hospital (BWH) and Rush University Medical Center, reveals how early changes in brain DNA methylation are involved in Alzheimer's disease. DNA methylation is a biochemical ...

Oncology & Cancer

Mobile DNA elements restructure cancer genomes

(Medical Xpress)—Researchers have found a novel mechanism that can restructure a cancer's genome and introduce hundreds of mutations. Previously overlooked through misidentification, this mechanism, a common feature of ...

Alzheimer's disease & dementia

Drug's effect on Alzheimer's may depend on severity of disease

A cancer drug that has shown promise against Alzheimer's disease in mice and has begun early clinical trials has yielded perplexing results in a novel mouse model of AD that mimics the genetics and pathology of the human ...

Genetics

Severe scoliosis linked to rare mutations

Children with rare mutations in two genes are about four times more likely to develop severe scoliosis than their peers with normal versions of the genes, scientists have found. The research at Washington University School ...

Psychology & Psychiatry

Rats, frosting helping find genetic causes of binge-eating

Two strains of rats, cans of vanilla frosting and a theory have helped MSU professor of psychology Kelly Klump take one step closer to finding the genetic causes, and eventually a treatment, for binge eating.

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