Genetics

Mutations that matter

(Medical Xpress)—Identifying the genetic source of a specific trait can be a little like finding a needle in a field full of haystacks. University of Dayton biologist Thomas Williams is working to shrink the number of haystacks.

Genetics

A genetic map for complex diseases

Although heavily studied, the specific genetic causes of "complex diseases," a category of disorders which includes autism, diabetes and heart disease, are largely unknown due to byzantine genetic and environmental interactions.

Medical research

Decoy FGFR3 protein appears to prevent dwarfism in mice

(Medical Xpress)—A team made up of researchers from several institutions in France has found that a decoy protein injected into mice, appears to prevent the development of dwarfism. In their paper published in the journal ...

Genetics

Lifestyle influences metabolism via DNA methylation

An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum München have now identified 28 DNA alterations associated with ...

Medical research

Host genome controls skin microbiota and inflammation

Numerous recent studies linked gut microbiota with various diseases such as obesity or diabetes. Little is known, however, on how gut and skin microbiota composition is controlled. In a recent study published in the journal ...

Addiction

Studies examine fetal alcohol syndrome in South Africa

Two recently published studies report prevalence data about fetal alcohol spectrum disorders (FASD) in South Africa and find that negative consequences of prenatal exposure to alcohol may be lessened if a child is provided ...

Oncology & Cancer

Why tumors become drug-resistant

Cancer drugs known as ErbB inhibitors have shown great success in treating many patients with lung, breast, colon and other types of cancer. However, ErbB drug resistance means that many other patients do not respond, and ...

Alzheimer's disease & dementia

Key molecular pathways leading to Alzheimer's identified

Key molecular pathways that ultimately lead to late-onset Alzheimer's disease, the most common form of the disorder, have been identified by researchers at Columbia University Medical Center (CUMC). The study, which used ...

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