A newly described form of stress called chromatin architectural defect, or chromatin stress, triggers in cells a response that leads to a longer life. Researchers at Baylor College of Medicine and the Houston Methodist Research ...
Jul 10, 2019
1
187
Nearly 10 years ago, a group of Israeli clinical researchers emailed Lawrence Berkeley National Laboratory (Berkeley Lab) geneticist Len Pennacchio to ask for his team's help in solving the mystery of a rare inherited disease ...
Jul 10, 2019
0
40
Scientists investigating heart failure have been limited to studying diseased heart tissue in the lab—understandably, as people don't tend to pluck out a healthy heart for the sake of research. But now, scientists with ...
Jun 24, 2019
0
1
Infectious proteins called prions cause a group of related, fatal and incurable neurodegenerative disorders, including bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt-Jakob disease, both of which affect ...
Jun 11, 2019
0
90
Congenital heart disease occurs in up to 1% of live births, and the infants who are affected may require multiple surgeries, life-long medication, or heart transplants. In many patients, the exact cause of congenital heart ...
May 30, 2019
0
57
A new study led by researchers from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard is the first to have observed the complex set of chemical and molecular events that disrupt the microbiome ...
May 29, 2019
0
82
Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials. However, other than observing clinical outcomes, lack of a repeatable, time-sensitive ...
May 22, 2019
0
109
New research from The Wistar Institute sheds light on the function of the ARID1A protein, encoded by a gene that is among the most frequently mutated across human cancers. According to the study, published online in Science ...
May 22, 2019
0
31
Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible ...
Apr 25, 2019
0
173
The ability of cancer to establish itself in distant parts of the body—called metastasis—causes 90% of deaths from solid tumors. Metastasis is the result of complex genetic interactions that have proven difficult for ...
Apr 9, 2019
0
20
