The story of the rise and fall of western equine encephalitis as a lethal disease offers essential lessons about how a pathogen can gain or lose its ability to jump from animals to humans.
Jul 25, 2024
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Scientists have uncovered that "gene misbehavior"—where genes are active when they were expected to be switched off—is a surprisingly common phenomenon in the healthy human population.
Jul 24, 2024
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From studying the human genome to analyzing the way proteins are encoded, or monitoring RNA expression, researchers are rapidly gaining a far richer understanding of the complex genetic and cellular mechanisms that underpin ...
Jul 24, 2024
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A new study by scientists at deCODE Genetics shows that sequence variants drive the correlation between DNA methylation and gene expression. The same variants are linked to various diseases and other human traits.
Jul 24, 2024
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Scientists at the University of Sydney and Liverpool School of Tropical Medicine have made a remarkable discovery: a commonly-used blood thinner, heparin, can be repurposed as an inexpensive antidote for cobra venom.
Jul 17, 2024
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While this concept may have been the norm hundreds of years ago, many present-day societies are overfed and undernourished, leading to floods of health issues in many populations. Getting back to the basics might be a large ...
Jul 15, 2024
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At Mayo Clinic, the mission to solve the unsolvable is at the heart of every rare disease case. Each diagnosis is a testament to perseverance, innovation and the relentless pursuit of answers.
Jun 24, 2024
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Between July and October 2023, highly pathogenic avian influenza (HPAI) A(H5N1) was detected in animals on 27 fur farms in Finland. The outbreak, traced to wild birds, revealed significant virus adaptation to mammals. The ...
Jun 21, 2024
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Human papillomavirus (HPV) is a pivotal etiological factor in the development of several cancers, with a profound impact on global public health. It is estimated that 50–70% of sexually active individuals are infected with ...
Jun 17, 2024
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Alternative splicing, a process where a single gene can give rise to multiple different proteins via inclusion or exclusion of certain segments of the gene sequence, is known to occur in over 90% of human genes. This leads ...
Jun 12, 2024
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The human genome is the genome of Homo sapiens, which is stored on 23 chromosome pairs. Twenty-two of these are autosomal chromosome pairs, while the remaining pair is sex-determining. The haploid human genome occupies a total of just over 3 billion DNA base pairs. The Human Genome Project (HGP) produced a reference sequence of the euchromatic human genome, which is used worldwide in biomedical sciences.
The haploid human genome contains an estimated 20,000–25,000 protein-coding genes, far fewer than had been expected before its sequencing. In fact, only about 1.5% of the genome codes for proteins, while the rest consists of RNA genes, regulatory sequences, introns and (controversially) "junk" DNA.
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