Genetics

Trillion data points to identify disease-causing genes

Researchers from CSIRO, Australia's national science agency, have accomplished a world-first by processing one trillion points of genomic data through VariantSpark, an artificial intelligence-based platform, which can help ...

Genetics

'Jumping' DNA regulates human neurons

The human genome contains over 4.5 million sequences of DNA called "transposable elements," virus-like entities that "jump" around and help regulate gene expression. They do this by binding transcription factors, which are ...

HIV & AIDS

Unique HIV reservoirs in elite controllers

Xu Yu, MD, Ragon group leader, recently published a study entitled "Distinct viral reservoirs in individuals with spontaneous control of HIV-1," in Nature. Yu's lab, in collaboration with Ragon group leaders Mathias Lichterfeld, ...

Oncology & Cancer

HPV strains may impact cervical cancer prognosis

An analysis of cervical cancers in Ugandan women has uncovered significant genomic differences between tumors caused by different strains of human papillomavirus (HPV), signifying HPV type may impact cervical cancer characteristics ...

Oncology & Cancer

Four-stranded DNA structures found to play role in breast cancer

Four stranded DNA structures—known as G-quadruplexes—have been shown to play a role in certain types of breast cancer for the first time, providing a potential new target for personalised medicine, say scientists at the ...

Diseases, Conditions, Syndromes

Insight on novel genetic approaches to metabolic liver diseases

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications. NAFLD affects over 30% of Americans, and is characterized as a fatty liver, which can progress ...

Genetics

Researchers generate complete human X chromosome sequence

Researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), have produced the first end-to-end DNA sequence of a human chromosome. The results, published today in ...

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