Immunology

Human rotavirus manipulates immune response to maintain infection

The gut of a child infected with rotavirus is like a battle ground. On one side, the virus invades the epithelial cells that form the lining of the small intestine. The virus replicates driving havoc in the intestinal environment, ...

Diseases, Conditions, Syndromes

Factors secreted by gut bacteria may help combat kidney stones

Researchers have discovered that factors secreted by gut bacteria might help prevent or treat kidney stones. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

Medical research

Gut model HuMiX works like the real thing

One of the most complex human organs is the digestive tract: Here, the body comes into contact with all manner of diet-derived compounds and with countless bacteria. Scientists from the Luxembourg Centre for Systems Biomedicine ...

Medical research

A cultural revolution in the study of the gut microbiome

It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst ...

Medical research

Lab-grown 3-D intestine regenerates gut lining in dogs

Working with gut stem cells from humans and mice, scientists from the Johns Hopkins Children's Center and the University of Pittsburgh have successfully grown healthy intestine atop a 3-D scaffold made of a substance used ...

Inflammatory disorders

Small intestine contributes to chronic inflammation in obesity

Obesity is caused by numerous and complex factors, some of which are as yet unsuspected. Scientists from the CNRS, INSERM, UPMC and Université Paris Descartes, working with research clinicians from Paris Public Hospitals ...

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