Researchers at Duke University have adapted CRISPR technologies for high-throughput screening of gene function in human immune cells and discovered that a single master regulator of the genome can be used to reprogram a network ...
Nov 9, 2023
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New research combining computer modeling and experiments with macaques shows the body's immune system helps control human immunodeficiency virus (HIV) infections largely by suppressing viral production in already infected ...
Nov 1, 2023
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RIKEN geneticists have developed a tool that can quickly and accurately analyze variants in mobile genetic elements, commonly known as "jumping genes." This promises to shed light on the role such variants play in disease.
Oct 31, 2023
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A group of ribosomal protein genes connect animal models of depression to human patients with major depressive disorder. In order to research depression treatments, scientists use a mouse model, inducing a state with similarities ...
Oct 11, 2023
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The aging brain undergoes structural and cellular changes that can impact function and increase susceptibility to neurodegenerative disorders like Alzheimer's disease. Age acceleration—or the differences between biological ...
Oct 10, 2023
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Cytokines are proteins that help the human body to control and support the work of the immune system. Over the past few decades, a growing number of studies have been exploring the role of specific cytokines, including IL-12, ...
Schizophrenia may be associated with the excessive formation of oversized and hyperactive synaptic connections between nerves in the brain, a mouse model and a human post-mortem study published in Science Advances by RIKEN ...
Oct 3, 2023
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Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion oncoproteins spontaneously form ...
Sep 28, 2023
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Researchers at the University of Michigan have developed a model for studying one type of familial epilepsy, opening the door to understanding—and eventually targeting—the mechanisms that lead to the disorder and its ...
Sep 25, 2023
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Brown adipocytes are specialized cells that can use energy to produce heat. This property makes them attractive tools for the treatment of diseases like obesity and type 2 diabetes. Until recently, this therapeutic potential ...
Sep 20, 2023
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