Genetic ablation of P2RX7 can improve muscle function and partially correct cognitive impairment and bone loss in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published this week in PLOS Medicine. ...
Oct 13, 2015
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Scientists at Duke University have released a highly detailed model of connections in the mouse brain that could provide generations of neuroscientists new insights into brain circuits and origins of mental illness, such ...
Sep 15, 2015
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Mice lacking the protein retGC1, which is deficient in humans suffering Leber congenital amaurosis-1 (LCA1), a disorder that causes severe visual impairment beginning in infancy, received gene therapy to replace retGC1 and ...
Aug 31, 2015
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Squamous cell carcinoma (SCC) of the skin is one of the most frequent cancers in humans affecting more than half million new persons every year in the world. The transformation of a normal cell to a cancer cell is caused ...
Jul 13, 2015
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Taking research from the lab to the clinic can be a long and arduous process, but necessary to ensure new therapeutic methods are safe. This typically involves models created in the lab to closely resemble the cellular mechanism ...
Jun 17, 2015
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Researchers at the Babraham Institute and the Francis Crick Institute have developed and used a new technique to join the dots in the genomic puzzle. Just as a dot to dot puzzle needs to be completed to visualise the full ...
May 4, 2015
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For couples struggling to conceive the old-fashioned way, in vitro fertilization (IVF) provides an alternate route to starting a family. When eggs are mixed with sperm in test tubes, the fertilized eggs to grow into embryos ...
Apr 28, 2015
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It is widely believed that learning is based on changes in the connections between nerve cells. Knowing the interconnections of nerve cells would considerably aid understanding of how the brain works. Scientists have pursued ...
Apr 14, 2015
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Most people have seen fMRI scans of the human brain. These use a technology called functional magnetic resonance imaging to identify portions of the brain that are active while a subject is being scanned. Fuzzy, ill-defined ...
Jan 5, 2015
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For decades, the mouse has been a mainstay for researchers studying human diseases because the two species share many of the same genes. But now, a comprehensive analysis of the inner workings of the DNA in humans and mice ...
Nov 20, 2014
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