Immunology

How the body's defenses keep their weapons in check

The signaling molecules of the immune system should trigger a response only where necessary. To prevent a life-threatening spread to the rest of the body, connective tissue can absorb these molecules like a sponge. A team ...

Diseases, Conditions, Syndromes

Vital new insights into deadly African sleeping sickness disease

A newly published extensive body of research into Human African trypanosomiasis (HAT), also known as sleeping sickness, has revealed new insights into the deadly parasitic disease that threatens the lives of millions of people ...

Oncology & Cancer

Probing the mechanism of ADAM28-mediated cancer metastasis

ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives ...

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