As a rare form of Lou Gehrig's disease paralyzes his body, Rodney Gorham hopes a pioneering link between his brain and a computer will help others after he is gone.
Aug 20, 2023
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University of California, Irvine biologists have developed a new genetically engineered mouse model, that unlike its predecessors, is based on the most common form of Alzheimer's disease. The advance holds promise for making ...
Apr 27, 2021
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Mice lacking the protein retGC1, which is deficient in humans suffering Leber congenital amaurosis-1 (LCA1), a disorder that causes severe visual impairment beginning in infancy, received gene therapy to replace retGC1 and ...
Aug 31, 2015
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When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are silent. Somehow, at an early stage of development, embryo genes must be switched on. Without this vital 'genes on' switch in the embryo, none ...
Feb 1, 2023
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Evidence in mouse and human brain tissue reveals a mechanism that may explain the sex-based differences in Alzheimer's disease, including why females are more vulnerable. Researchers report October 4 in the journal Cell that ...
Oct 4, 2022
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Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that overactivation of the RANK signalling pathway promotes the initiation, progression and metastasis of tumours in human breast epithelial ...
Apr 24, 2012
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A targeted gene silencing strategy blocks production of the dysfunctional huntingtin (Htt) protein, the cause of Huntington's disease, a fatal, inherited neurodegenerative disorder. The effectiveness of this RNA interference ...
May 21, 2014
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Squamous cell carcinoma (SCC) of the skin is one of the most frequent cancers in humans affecting more than half million new persons every year in the world. The transformation of a normal cell to a cancer cell is caused ...
Jul 13, 2015
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Experts in cell signaling at the Babraham Institute have identified how prostate cancer cells achieve cell growth free from the usual growth cues and regulators. This discovery has implications for potential therapeutics ...
Sep 11, 2023
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Tumor cells often express proteins that set them apart from their healthy neighbors. These very same proteins can also help the immune system to recognize and destroy the cancer. Several research groups and companies have ...
Apr 26, 2013
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