Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue ...
Feb 11, 2013
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Imagine a type of personalized treatment where mice serve as surrogates to treat human disease.
May 20, 2014
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National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced. The new mouse model shows milder cognitive traits compared ...
Mar 14, 2023
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Researchers at the Paris Cardiovascular Research Center (PARCC) have shown how adhesion of Neisseria (N.) meningitidis to human microvessels in a humanized mouse model leads to the characteristic cutaneous lesions of meningococcal ...
Jan 24, 2013
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For decades, the mouse has been a mainstay for researchers studying human diseases because the two species share many of the same genes. But now, a comprehensive analysis of the inner workings of the DNA in humans and mice ...
Nov 20, 2014
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Every few weeks or months, the media reports on a new study that tantalizingly dangles the possibility of a new drug to give us longer, healthier lives.
Jul 25, 2024
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Aicardi-Goutieres syndrome is a rare disease that can trigger dementia in children. Associate Professor Markus Hofer and colleagues in the U.K. are focusing on treatments in the blood vessels in the brain to combat AGS.
Jun 26, 2024
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Researchers from Tokyo Medical and Dental University (TMDU) have found that donor keratinocytes injected into mouse embryos form sheets of epidermis that can be used as autologous skin grafts.
May 29, 2024
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The candidate gene FKBP5 is involved in the development of stress-related psychiatric disorders. A few years ago, researchers at the MPI discovered that it is increasingly activated in the brains of patients and can permanently ...
Feb 27, 2024
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In a new publication that appears in Human Molecular Genetics, the laboratory of Christine DiDonato, PhD reports on their pharmacological characterization of the drug RG3039, demonstrating that it can extend survival and ...
Jun 4, 2013
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