Genetics

Transgenic mice ready to fight obesity—and more

Scientists at the Nencki Institute of Experimental Biology of the Polish Academy of Sciences in Warsaw investigate mice with a very precisely modified genome. Because it is possible to turn off the Dicer gene in adult mice, ...

Diseases, Conditions, Syndromes

'Humanized' liver in mice reveals roots of chronic diseases

Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting ...

Psychology & Psychiatry

Exploring the ribosome–depression link

A group of ribosomal protein genes connect animal models of depression to human patients with major depressive disorder. In order to research depression treatments, scientists use a mouse model, inducing a state with similarities ...

Medical research

Mice with 'humanized' livers improve early drug testing

Stanford University School of Medicine scientists have used bioengineered mice with livers composed largely of human cells to characterize a drug about to enter early-stage clinical development for combating hepatitis C.

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