Squamous cell carcinoma (SCC) of the skin is one of the most frequent cancers in humans affecting more than half million new persons every year in the world. The transformation of a normal cell to a cancer cell is caused ...
Jul 13, 2015
0
28
For decades, the mouse has been a mainstay for researchers studying human diseases because the two species share many of the same genes. But now, a comprehensive analysis of the inner workings of the DNA in humans and mice ...
Nov 20, 2014
0
0
The Malt1 protein is one of the most important control centers in human immune cells and a real all-rounder. Genetic defects in it can lead to the development of lymphatic cancer (lymphoma). A possible therapeutic approach ...
Nov 17, 2014
0
0
Geneticists at Heidelberg University Hospital's Department of Molecular Human Genetics have used a new mouse model to demonstrate the way a certain genetic mutation is linked to a type of autism in humans and affects brain ...
Nov 12, 2014
0
0
In the earliest moments of a mammal's life, the developing ball of cells formed shortly after fertilisation 'does as mother says' – it follows a course that has been pre-programmed in the egg by the mother. Extraordinary ...
Oct 30, 2014
0
0
Scientists at The University of Manchester have used a new way of working to identify a new gene linked to neurodegenerative diseases such as Alzheimer's. The discovery fills in another piece of the jigsaw when it comes to ...
Oct 9, 2014
0
1
(Medical Xpress)—A new mouse model of osteogenic sarcoma, a potentially deadly form of bone cancer, shows that high levels of Notch1, a gene that helps determine cell fate, can drive osteoblasts (cells that normally lead ...
Sep 8, 2014
0
0
Mouse models of human diseases are essential research tools that are widely used in the medical sciences to increase our understanding of the pathogenesis and pathophysiology of various diseases, and to search for cures. ...
Aug 4, 2014
0
0
Imagine a type of personalized treatment where mice serve as surrogates to treat human disease.
May 20, 2014
0
0
(Medical Xpress)—Research from Western University has revealed a possible new target for treating movement disorders such as Huntington's disease (HD) and Parkinson's disease. Stephen Ferguson, PhD, a scientist at Western's ...
Mar 14, 2014
0
1
