Medical research

Obese inducing brain mechanism

Leptin is an adipocyte-derived hormone that stimulates hypothalamic neurons to strongly inhibit food intake. Leptin signaling in the hypothalamus, a part of the mid-brain, thus plays a crucial role in the regulation of body ...

Neuroscience

Manipulating a single gene defines a new pathway to anxiety

Removing a single gene from the brains of mice and zebrafish causes these animals to become more anxious than normal. Researchers from University of Utah Health show that eliminating the gene encoding Lef1 disrupts the development ...

Medical research

Brain cells found to control aging

Scientists at Albert Einstein College of Medicine have found that stem cells in the brain's hypothalamus govern how fast aging occurs in the body. The finding, made in mice, could lead to new strategies for warding off age-related ...

Neuroscience

Brain's immune cells may drive overeating and weight gain

Immune cells in the brain trigger overeating and weight gain in response to diets rich in fat, according to a new study in mice led by researchers from UC San Francisco and the University of Washington Medical Center, and ...

Neuroscience

Hypothalamus neurons modulate pancreatic insulin amounts

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of POMC neurons in the hypothalamus that detect and integrate signals related to the body's energy state and ...

Neuroscience

Research identifies brain cells that keep mice active

Scientists have discovered a type of brain cell that prevents mice from being overly immobile. The research provides insight into the brain circuits underlying what motivates us to be physically active.

Neuroscience

Gamma oscillations coordinate food seeking

Food seeking is a crucial survival instinct. However, until recently, little was known about how the brain regulates this behavior. Scientists at the Leibniz-Institut für Molekulare Pharmakologie (FMP) and NeuroCure Cluster ...

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