Medical research

Hypoxia reverses mitochondrial disease in mouse model

The next stage of a Massachusetts General Hospital (MGH) team's investigation into the therapeutic potential of the hypoxia response - the body's reaction to reduced levels of oxygen in the blood - to treat mitochondrial ...

Oncology & Cancer

Study reveals how melanoma spreads

Cancerous tumors are voracious. Once they have consumed all the oxygen and nutrients in the original tumor site, the cancer cells travel to other parts of the body (metastasize) to find more nourishment.

Oncology & Cancer

The antibody that normalizes tumor vessels

An important parcel must be delivered to the correct place. It is so important that it can be a question of life or death. However, uneven streets and missing railings risk to bring it off the road and leave it undelivered. ...

Oncology & Cancer

Research on HIF-2 featured in Nature, Structure

New insights into the potential for new classes of HIF inhibitors to restore control of the hypoxia response—representing the potential foundation of a new cancer-fighting strategy—are the focus of recently published ...

Sleep disorders

How a bad night's sleep might worsen cancer development

Recent studies have indicated that patients with sleep apnea may be associated with worse cancer outcomes. Now a new animal study, presented at the European Association of Urology Congress in Munich, uncovers a possible mechanism ...

Neuroscience

Seizures from solving sudoku puzzles

The JAMA Neurology feature "Images in Neurology" features the case of a 25-year-old right-handed physical education student who was buried by an avalanche during a ski tour and endured 15 minutes of hypoxia (oxygen deficiency).

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