Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, a research team is testing drugs that activate STING as a form of cancer immunotherapy and for treating certain infections. Findings from ...
Aug 10, 2022
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Studying the complex causes of Alzheimer's disease, and how to treat and prevent this condition, is like solving a many-piece puzzle, with scientists each tackling a small section, unsure of how it might fit into the larger ...
Oct 26, 2021
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Patients with multiple sclerosis have higher rates of depression than the general population, including people with other life-long disabling diseases. Symptoms of multiple sclerosis arise from an abnormal response of the ...
Jul 7, 2016
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The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal ...
Apr 7, 2013
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Immune checkpoint inhibitors have revolutionized cancer care. The therapy works by preventing tumors from shutting down the immune response, which in turn allows T cells to kill cancer cells. Established checkpoint inhibitors ...
Jun 27, 2022
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More and more hospitalized patients with sepsis are being diagnosed with a deadly complication characterized by high levels of inflammation. A team of Yale researchers has uncovered clues to the cause of this complication—which ...
Feb 11, 2019
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A new study from the University of Toronto's Faculty of Kinesiology & Physical Education has found that moderate to vigorous physical activity may help regulate the levels of C-reactive protein – an important biomarker ...
May 25, 2018
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Combination antiretroviral therapy (cART) suppresses HIV replication and significantly slows the progression of disease, enabling HIV+ individuals to effectively manage infection for long periods. One of the manifestations ...
Jul 7, 2016
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Many tumor cells mist themselves with a protective perfume that disables the immune system. But a drug already approved for other purposes can apparently render this weapon harmless. This is shown in a study by the University ...
Aug 24, 2022
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A new study published in Physiological Genomics suggests that the brain shows signs of aging earlier than old age. The study found that the microglia cells—the immune cells of the brain—in middle-aged mice already showed ...
Mar 18, 2016
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