Immunology

Enzyme lays the foundations for allergic immune response

While in search of the causes of allergies and asthma, a chance discovery has yielded new clues: researchers led by Dr. Marcus Peters have ascertained that the enzyme guanylate cyclase in cells lays the foundations for the ...

Diseases, Conditions, Syndromes

Study provides insights on immune cells involved in kidney disease

Researchers have uncovered new information on cells involved in the body's immune response following kidney injury. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), ...

Oncology & Cancer

Study links obesity with dampened immune detection of oral cancers

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the ...

Inflammatory disorders

New research defines role of long noncoding RNAs in inflammation

Inflammation and immune system activation are complex processes controlled by elaborate signaling pathways and hundreds of genes that are turned on and off in response to external stimuli such as bacteria or viruses. A class ...

Oncology & Cancer

A stem cell protein facilitates relapse of pediatric brain tumors

Medulloblastoma is the most common form of malignant brain tumor in children, which often can be cured with operation, radiation and chemotherapy. But a distinct type of medulloblastoma has an increased risk of becoming resistant ...

Oncology & Cancer

New discovery would allow researchers to fine-tune CAR-T activity

A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease ...

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