Immunology

Hunger-spiking neurons could help control autoimmune diseases

Neurons that control hunger in the central nervous system also regulate immune cell functions, implicating eating behavior as a defense against infections and autoimmune disease development, Yale School of Medicine researchers ...

HIV & AIDS

Scientists discover how HIV kills immune cells

Untreated HIV infection destroys a person's immune system by killing infection-fighting cells, but precisely when and how HIV wreaks this destruction has been a mystery until now. New research by scientists at the National ...

Medical research

Novel therapy improves immune function in teen with rare disease

In a novel approach that works around the gene defect in Wiskott-Aldrich syndrome, an inherited immune deficiency disorder, researchers used an alternative cell signaling pathway to significantly improve immune function in ...

Immunology

Engineering the immune system to kill cancer cells

In late 2015, former President Jimmy Carter announced that he was free of the metastatic melanoma that had spread to his liver and brain. In addition to surgery and radiation, Carter was treated with an immunotherapy drug, ...

Medical research

Controlling cell death prevents skin inflammation

The outer layer of the skin, called the epidermis, forms a critical physical and immunological wall that serves as the body's first line of defense against potentially harmful microorganisms. Most of the epidermis consists ...

Parkinson's & Movement disorders

Study raises possibility of immunotherapy treatment for ALS

New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease.

Immunology

How the thymus trains T cells to fight infections

T cells are a special class of white blood cells that patrol the body and attack infected or foreign tissue. They learn to distinguish friendly proteins from dangerous ones in an organ called the thymus. However, when T cells ...

Cardiology

Doxorubicin disrupts the immune system to cause heart toxicity

Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart ...

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