Medical research

Alveolar macrophages help CD8+ T cells go (anti-)viral

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues. Now, researchers from Japan ...

Oncology & Cancer

Why don't T cells destroy solid tumors during immunotherapy?

The great hope of cancer immunotherapy is to bolster our own immune cells in specific ways to keep cancer cells from evading our immune system. Although much progress has been made, immunotherapy does not always work well. ...

Oncology & Cancer

Examining resistance to immunotherapy in ovarian cancer

A team at Memorial Sloan Kettering Cancer Center (MSK) has uncovered several mechanisms of immune escape that can help explain why ovarian cancers have been resistant to immunotherapy to date.

Immunology

Common immune cells found to sometimes prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, ...

Diseases, Conditions, Syndromes

CAR T cell therapy could reach beyond cancer

Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers. Now, investigators have reported highly promising early results for CAR T therapy in a small ...

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