Oncology & Cancer

Sensory nerves appear to drive head and neck cancer growth

Researchers at the University of Colorado Anschutz Medical Campus studying interactions between nerves and tumor microenvironments have found that commonly used drugs like botox may stop or slow the progression of certain ...

Oncology & Cancer

How early-stage cancer cells hide from the immune system

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance and develop into more advanced tumors.

Immunology

The 'switch' that keeps the immune system from attacking the body

A microscopic battle rages in our bodies, as our cells constantly fend off invaders through our immune system: a complex system of cells and proteins designed to protect us from harmful pathogens. One of its central components ...

Immunology

Review discusses metabolic reprogramming of T cells

When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...

Oncology & Cancer

Enzyme checkpoint identified in tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic checkpoint ...

Oncology & Cancer

Predicting immunotherapy success via biomarkers

Researchers at the Technion's Ruth and Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences have discovered a subset of blood cells that predict the success of immunotherapy ...

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