Although metastatic castration-resistant prostate cancer (mCRPC) typically has limited response to immunotherapy, a subset of patients with pretreatment evidence of active T-cell responses in their tumors experienced prolonged ...
Apr 1, 2020
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144
In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven't ...
Mar 19, 2020
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53
Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according ...
Feb 21, 2020
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183
You awake in the middle of the night from a nightmare.
Feb 10, 2020
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An interdisciplinary team of researchers at the UCLA Jonsson Comprehensive Cancer Center has developed a medicated patch that can deliver immune checkpoint inhibitors and cold plasma directly to tumors to help boost the immune ...
Feb 3, 2020
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215
Researchers at Johns Hopkins Kimmel Cancer Center, the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine have developed an integrated genomic approach that potentially ...
Jan 15, 2020
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92
Many liver cancer tumors contain a highly diverse set of cells, a phenomenon known as intra-tumor heterogeneity that can significantly affect the rate at which the cancer grows, Mount Sinai researchers report. The immune ...
Jan 15, 2020
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86
Immune checkpoint inhibitors are important medications that boost the immune system's response against certain cancers; however, they tend to be ineffective against glioblastoma, the most deadly primary brain tumor in adults. ...
Dec 23, 2019
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136
After a cancer patient receiving an immunotherapy developed encephalitis and died 18 months into treatment, researchers at Vanderbilt-Ingram Cancer Center (VICC) investigated why the complication occurred, performing a molecular ...
Jul 22, 2019
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140
St. Jude Children's Research Hospital scientists have evidence that children with acute lymphoblastic leukemia mount a robust immune response to their cancer. The findings, which appear today in the journal Science Translational ...
Jun 26, 2019
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