Arthritis & Rheumatism

Gum disease may lie at the root of some arthritis flareups

It's a well-documented medical mystery: Patients with gum disease are less likely to respond to rheumatoid arthritis treatments. But new research may help explain this link between gum disease and an otherwise disparate condition. ...

Genetics

3D genome architecture influences SCID-X1 gene therapy success

Patients with X-linked severe combined immunodeficiency disorder (SCID-X1), sometimes called "bubble boy disease," are born with a defective gene that prevents them from producing immune cells. Gene therapy from St. Jude ...

Gastroenterology

Optimization of human small intestinal organoids

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids—miniature versions of the small intestine. This will help them to better study the functioning of the small ...

Immunology

A common metabolite may help treat autoimmune diseases

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

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