The population's immunity to SARS-CoV-2, achieved either through infection or vaccination, is crucial to overcome the COVID-19 pandemic. A team of researchers led by the University of Zurich (UZH) has now discovered another ...
Nov 22, 2021
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The immune system uses its mitochondria to self-stimulate innate and adaptive responses to infection. Reactive oxygen species (ROS), immunogenic mitochondrial DNA (mtDNA), and even whole mitochondria are locally mobilized ...
A human immune system is a lot like the board game Mouse Trap: it's a Rube Goldberg system of interacting parts. Only instead of a falling ball causing a tiny diver to leap into a tub—which, in turn, springs a trap on some ...
Mar 22, 2022
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An interdisciplinary team of researchers at the UCLA Jonsson Comprehensive Cancer Center has developed a medicated patch that can deliver immune checkpoint inhibitors and cold plasma directly to tumors to help boost the immune ...
Feb 3, 2020
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A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen ...
Apr 13, 2020
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Scientists at the Luxembourg Institute of Health (LIH) have discovered hitherto unknown molecular mechanism by which the human immune system activates its immune cells. T cells that express a gene known as Gclc effectively ...
Apr 19, 2017
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An attack of gout is said to be like your joint catching fire, and someone slamming it with a hammer to put out the flames. Now A*STAR researchers have identified how the build-up of monosodium urate (MSU) crystals in the ...
Sep 20, 2017
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We age in part thanks to "friendly fire" from the immune system—inflammation and chemically active molecules called reactive oxygen species that help fight infection, but also wreak molecular havoc over time, contributing ...
Apr 7, 2015
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Macrophages are best known for their Pac Man-like ability to gobble up cellular debris and pathogens in order to thwart infection. A new study in The Journal of Cell Biology describes how these immune cells also help resolve ...
Dec 8, 2014
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In salt-sensitive hypertension, immune cells gather in the kidneys and shoot out free radicals, heightening blood pressure and damaging this pair of vital organs, scientists report.
Feb 11, 2020
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