Immunology

Molecular interplay explains many immunodeficiencies

Australian scientists have described an exquisitely balanced interplay of four molecules that trigger and govern antibody production in immune cells. As well as being an important basic science discovery, it helps explain ...

Immunology

Study shows how Staph toxin disarms the immune system

Researchers at NYU Langone Medical Center have discovered a new mechanism by which the deadly Staphylococcus aureus bacteria attack and kill off immune cells. Their findings, published today in the journal Cell Host & Microbe, ...

Medical research

How JC Polyomavirus invades cells

For more than a decade the research group of Brown University Professor Walter Atwood has doggedly pursued the workings of the JC polyomavirus, which causes a disease called PML that fatally degrades the central nervous system ...

HIV & AIDS

How HIV infects cells

In a long-awaited finding, an international team of scientists using high-brightness x-rays from the U.S. Department of Energy Office of Science's Advanced Photon Source at Argonne National Laboratory has determined the high-resolution ...

HIV & AIDS

Molecular structure reveals how HIV infects cells

In a long-awaited finding, a team of Chinese and US scientists has determined the high-resolution atomic structure of a cell-surface receptor that most strains of HIV use to get into human immune cells. The researchers also ...

Medical research

Lung disease and melanoma: A common molecular mechanism?

A Yale-led team of researchers has solved a biological mystery about the common genesis of many serious diseases such as asthma and metastatic melanoma, identifying the first known pathway by which their cellular functions ...

Immunology

Rapid recall to fight familiar foes

The immune system's first encounter with a potential threat is a valuable learning experience. Through a process of genetic recombination, our immune B cells can potentially produce a wide array of B cell receptor (BCR) molecules, ...

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