Medical research
Infection-fighting B cells go with the flow
Newly formed B cells take the easy way out when it comes to exiting the bone marrow, according to a study published in The Journal of Experimental Medicine.
Nov 17, 2014
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Page 22 - News tagged with immune receptors
Immunology
Connective tissue protein fights bacterial infection
A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition called sepsis, a new study ...
Jun 28, 2021
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Oncology & Cancer
'Dual-target' cell therapy appears to shrink brain tumors, research finds
Targeting two brain tumor-associated proteins—rather than one—with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain ...
Mar 13, 2024
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Immunology
Study shows how Staph toxin disarms the immune system
Researchers at NYU Langone Medical Center have discovered a new mechanism by which the deadly Staphylococcus aureus bacteria attack and kill off immune cells. Their findings, published today in the journal Cell Host & Microbe, ...
Oct 16, 2013
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Immunology
Immune receptors amplify 'invader' signals by turning into mini-machines
When a receptor on the surface of a T cell—a sentry of the human immune system—senses a single particle from a harmful intruder, it immediately kicks the cell into action, launching a larger immune response. But exactly ...
Nov 21, 2016
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Oncology & Cancer
Risk of secondary cancers after CAR-T cell therapy low, according to large study
A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy—a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable ...
Jun 12, 2024
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Immunology
How gut bacteria evade the immune system
Researchers from the Max Planck Institute for Biology Tübingen address the long-standing question of how benign gut microbes evade the immune system. In doing so, they also reshape our understanding of how immune receptors ...
Jan 12, 2023
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Oncology & Cancer
Immunotherapy with two novel drugs shows activity in colorectal cancer
A combination of two next-generation immunotherapy drugs has shown promising clinical activity in treating patients with refractory metastatic colorectal cancer, a disease which has not previously responded well to immunotherapies, ...
Jan 23, 2023
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Oncology & Cancer
Natural killers: Using the body's cells to target breast cancer
It sounds like a plot from a Quentin Tarantino movie—something sets off natural killers and sends them on a killing spree.
Jun 16, 2021
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Oncology & Cancer
Specific components of the tumor immune microenvironment may affect responses to BCMA CAR T-cell therapy
Patients with myeloma whose tumor immune microenvironments had a more diverse baseline T-cell repertoire, fewer markers of immune cell exhaustion, and distinct changes to immune cell populations were more likely to have longer ...
Aug 30, 2022
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