Developing a vaccine is difficult at the best of times, but rarely have we been in a situation where basic knowledge about a virus has to be acquired so directly alongside the race to eradicate it. To understand how difficult ...
Jun 11, 2020
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T cell receptors are an important part of the human immune system. They are able to switch their conformation from an inactive to an active state spontaneously without any antigens present. Cholesterol binds and stabilizes ...
May 27, 2016
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A therapy that bolsters the immune system may not only help certain cancer patients live longer, but better, a new study finds.
Apr 5, 2023
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A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress ...
May 18, 2016
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The inflammatory response is a double-edged sword—it enables the body to mount a vigorous defense against infection, but can also inflict serious physiological damage if allowed to rampage uncontrolled. Patients experience ...
Sep 26, 2012
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Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors—an advance ...
May 8, 2024
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A new discovery in mice may lead to new treatments that could make bone marrow transplants more likely to succeed and to be significantly less dangerous. According to new research findings published in the Journal of Leukocyte ...
Apr 1, 2012
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T cells are usually good at eliminating diseased cells, but they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, and how ...
Jun 13, 2022
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Researchers at Houston Methodist demonstrated that a surface protein called OX40, responsible for keeping one type of immune system cell alive, can trigger the death of liver immune cells, in turn starting a chain reaction ...
Apr 24, 2017
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Modulation of neuroreceptors can stop the growth of lung carcinoma (cancer) cells, according to a recent study conducted by a group of researchers from the Institute of Bioorganic Chemistry of the Russian Academy of Sciences ...
Aug 15, 2019
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