Immunology

Counting the seconds for immunological tolerance

Our immune system must distinguish between self and foreign and in order to fight infections without damaging the body's own cells at the same time. The immune system is loyal to cells in the body, but how this works is not ...

Oncology & Cancer

Cancer vaccine could use immune system to fight tumors

Cincinnati Cancer Center (CCC) and UC Cancer Institute researchers have found that a vaccine, targeting tumors that produce a certain protein and receptor responsible for communication between cells and the body's immune ...

Immunology

Molecular interplay explains many immunodeficiencies

Australian scientists have described an exquisitely balanced interplay of four molecules that trigger and govern antibody production in immune cells. As well as being an important basic science discovery, it helps explain ...

Medical research

How JC Polyomavirus invades cells

For more than a decade the research group of Brown University Professor Walter Atwood has doggedly pursued the workings of the JC polyomavirus, which causes a disease called PML that fatally degrades the central nervous system ...

Medical research

Lung disease and melanoma: A common molecular mechanism?

A Yale-led team of researchers has solved a biological mystery about the common genesis of many serious diseases such as asthma and metastatic melanoma, identifying the first known pathway by which their cellular functions ...

Immunology

Rapid recall to fight familiar foes

The immune system's first encounter with a potential threat is a valuable learning experience. Through a process of genetic recombination, our immune B cells can potentially produce a wide array of B cell receptor (BCR) molecules, ...

Medical research

Molecular imaging finds hurdle for smokers' vaccine

Researchers have yet again been sent back to the drawing board in the development of the much-sought-after vaccination for smokers, which would hypothetically inhibit the action of nicotine and its pleasure-producing chemical ...

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