Immunology

ANCA-associated vasculitis: The ADVOCATE study

ANCA-associated vasculitis (AAV) is a systemic disease involving the formation of special autoantibodies (so-called anti-neutrophil cytoplasmic antibodies/ANCA) and vascular inflammation. There are several diseases associated ...

Immunology

Immune-related adverse events up with checkpoint inhibitors

(HealthDay)—Although patients with pre-existing autoimmune disease who receive checkpoint inhibitors (CPIs) are at risk for exacerbation of their disease, immune-related adverse events (irAEs), or both, events can often ...

Oncology & Cancer

Single-dose PCV13 immunogenic, safe in pediatric oncology

(HealthDay)—For pediatric and adolescent oncology patients, a single-dose 13-valent pneumococcal conjugate vaccine (PCV13) is safe and immunogenic, according to a study published online July 11 in Cancer.

Immunology

Addition of immunosuppression no benefit in IgA nephropathy

(HealthDay)—For patients with immunoglobulin A (IgA) nephropathy, the addition of immunosuppressive therapy to intensive supportive care does not improve outcomes, according to a study published in the Dec. 3 issue of the ...

Diseases, Conditions, Syndromes

Roundworm infections threaten organ recipients

(HealthDay)—Three people who received transplant organs in 2012 from the same 24-year-old donor got more than they bargained for: Each developed a severe roundworm infection, U.S. health officials reported Thursday.

Diseases, Conditions, Syndromes

Immunosuppressant response predicts aplastic anemia survival

(HealthDay)—Response to immunosuppressive therapy (IST) predicts overall survival (OS) in aplastic anemia (AA), according to a study published online Aug. 29 in the American Journal of Hematology.

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