Medical research

Restoration of immune defense in liver disease

Patients suffering from chronic liver disease don't respond to vaccination and are at high risk of viral infections. In these patients, virus-specific T-cells are defect and unable to eliminate viral pathogens. A research ...

Diseases, Conditions, Syndromes

Sepsis: The hidden killer

Sepsis has a way of flying under the radar. Public awareness of the life-threatening disease is low, and official statistics are misleading. Now researchers are using special alarm systems and AI to increase detection.

Genetics

Study identifies the human genes enabling SARS-CoV-2 infection

The activity of a gene called CIART is a key factor in the establishment of the viral infection that causes COVID-19, according to a study from researchers at Weill Cornell Medicine and New York University Grossman School ...

HIV & AIDS

Identifying where HIV sleeps in the brain

The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent infections. The role of the structure ...

Immunology

Molecular component of caffeine may play a role in gut health

Brigham researchers studying how and why certain cell types proliferate in the gut found that xanthine, which is found in coffee, tea and chocolate, may play a role in Th17 differentiation. Insights may help investigators ...

Immunology

Immune cells hold clues to vitamin D absorption, study suggests

Vitamin D plays an integral role in regulating immune function, and Penn State researchers have identified immune cells in mice that can be differentiated by whether or not they have vitamin D receptors—a finding that could ...

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