Medical research

Impact of prion proteins on the nerves revealed for the first time

When prion proteins mutate, they trigger mad cow and Creutzfeldt-Jakob disease. Although they are found in virtually every organism, the function of these proteins remained unclear. Researchers from the University of Zurich ...

Medical research

New drug offers hope in fight against mad cow disease

A new drug compound could lead to a breakthrough in the fight against bovine spongiform encephalopathy, the incurable brain-wasting disease also known as mad cow disease, researchers said Wednesday.

Medical research

Prion protein protects against epilepsy

In the most systematic and rigorous study conducted thus far in its field, the prion protein (PrPC) was clearly shown to play a role in preventing the onset of epileptic seizures. PrPC is perhaps best known in its 'degenerate' ...

Medical research

The flexible tail of the prion protein poisons brain cells

For decades, there has been no answer to the question of why the altered prion protein is poisonous to brain cells. Neuropathologists from the University of Zurich and University Hospital Zurich have now shown that it is ...

Medical research

New approach to protecting prion protein from altering shape

A team of researchers from Case Western Reserve University School of Medicine have identified a mechanism that can prevent the normal prion protein from changing its molecular shape into the abnormal form responsible for ...

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